SKULPT – 250mcg tablet

SLU-PP-332 is a small-molecule research compound examined in laboratory settings for its interaction with estrogen-related receptor alpha (ERRα), a nuclear receptor involved in regulating genes associated with mitochondrial function and cellular energy metabolism. In laboratory models, SLU-PP-332 has been shown to bind to the ligand-binding domain of ERRα, promoting receptor activation and interaction with transcriptional coactivators such as PGC-1α.

In research literature, this interaction shows SLU-PP-332 is utilized as a tool to study ERR-dependent transcriptional programs, including pathways associated with oxidative metabolism, mitochondrial biogenesis, and cellular energy utilization.

In skeletal muscle models, SLU-PP-332 induces oxidative fiber transitions and increases respiratory capacity comparable to exercise-training signatures. Preclinical studies show systemic metabolic shifts toward fatty acid oxidation, increased energy expenditure, and improved mitochondrial function in stressed tissues.